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Chinese, U.S. scientists identify two ges related to ovarian

作者:admin 来源:未知 更新日期:2020-02-14 浏览次数:

  
 

   WASHINGTON,thatcouldbeusedasbiomarkersandpointtotherapeutictargetsfordiagnosingandtreatingfemaleinfertilityandage-associatedovariandiseases,suchasovariancancer,,601ovariancellsfromyoungandoldnon-humanprimates,andidentifiedgeneactivitypatternsforeverytypeofprimateovariancellincludingooctyesandgranulosacells,whichsurroundtheoocytesastheydevelop."Ourgoalwastoanalyzeeachovariancelltypealongwithpatternsingeneexpressioninordertobetterunderstandexactlyhowovariesage,"saidthepapersco-correspondingauthorQuJingwiththeChineseAcademyofSciences."Thissystematicapproachprovidesabetterunderstandingofthemechanismsofhealthyovarianaging."Astheprimateovariancellsaged,someofthegenesthatfightcellularstressbecamelessactivewhichledtodamageandimpairmentinfunction,(IDH1andNDUFB10),theytestedwhathappe,herapeutictargetsforthediagnosisandtreatmentofage-relateddeclineoftheovaries."Ourresultswillhopefullyleadtothedevelopmentofnewtoolstoaidintherejuvenationofagedovariancells,"saidLiuGuanghuiwithInstituteofBiophysicsoftheChineseAcademyofSciences.。

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